Bempedoic Acid

1. Side effects of Bepeditic acid are present in the liver, without skeletal muscle side effects. There are questions about the safety of drugs. ACSVL1, which is decomposed into active metabolites of Bempedoic acid, is a liver-specific enzyme that exists only in the liver but not in skeletal muscle. Bempedoic acid has no skeletal muscle side effects of statins, which is also one of the bases for the combination of Bempedoic acid and statins.

2. Combination drug: Nexlizet is the first non-statins, cholesterol-lowering (LDL-C) combination drug to receive regulatory approval;

3. Oral lipid-lowering drug approval for the first time: Nexletol is the first oral, once-a-day, non-statins, cholesterol-lowering (LDL-C) drug that has been approved by regulators in the past 20 years, and it has a new mechanism of action in ldL-C reduction.