1. Product information
Names
| Name | tert-butyl n-(2-hydroxyethyl)carbamate |
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| Synonym | More Synonyms |
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Boc-NH-PEG1-OH Biological Activity
| Description | Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 267.2±23.0 °C at 760 mmHg |
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| Molecular Formula | C7H15NO3 |
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| Molecular Weight | 161.199 |
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| Flash Point | 115.4±22.6 °C |
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| Exact Mass | 161.105194 |
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| PSA | 58.56000 |
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| LogP | 0.49 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.450 |
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| Storage condition | 2-8°C |
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MSDS
Boc-NH-PEG1-OH MSDS(Chinese) |
Safety Information
| Symbol |  
GHS05, GHS06 |
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| Signal Word | Danger |
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| Hazard Statements | H301-H315-H318-H335 |
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| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338 |
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| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | T:Toxic; |
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| Risk Phrases | R25;R37/38;R41 |
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| Safety Phrases | S26-S39-S45-S36/37/39 |
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| RIDADR | UN 2810 6.1/PG 3 |
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| WGK Germany | 3 |
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| Hazard Class | 6.1 |
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| HS Code | 2924199090 |
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2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
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