1. Materials information
Names
Name | 1,4,7,10-tetraazacyclododecane |
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Synonym | More Synonyms |
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Cyclen Biological Activity
Description | Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates[1]. |
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Related Catalog | Research Areas >> Others Signaling Pathways >> Others >> Others |
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References | [1]. Rashid HU, et al. Cyclen-based Gd3+ complexes as MRI contrast agents: Relaxivity enhancement and ligand design. Bioorg Med Chem. 2016 Nov 15;24(22):5663-5684. |
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Chemical & Physical Properties
Density | 0.9±0.1 g/cm3 |
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Boiling Point | 283.8±8.0 °C at 760 mmHg |
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Melting Point | 110-113 °C(lit.) |
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Molecular Formula | C8H20N4 |
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Molecular Weight | 172.27 |
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Flash Point | 129.5±13.5 °C |
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Exact Mass | 172.168793 |
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PSA | 48.12000 |
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LogP | -2.34 |
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Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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Index of Refraction | 1.424 |
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Storage condition | Refrigerator |
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Toxicological Information
CHEMICAL IDENTIFICATIONCAS REGISTRY NUMBER : 294-90-6
MOLECULAR FORMULA : C8-H20-N4
HEALTH HAZARD DATAACUTE TOXICITY DATAROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
REFERENCE : NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year: 70,201,1983
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 19,425,1984
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
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