1. Product information
Names
Name | caesium chloride |
---|
Synonym | More Synonyms |
---|
Cesium chloride Biological Activity
Description | Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na+ transport produced by Alloxan[1][2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models[3]. |
---|
Related Catalog | Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel |
---|
In Vitro | Cesium chloride (CsCl) decreases the increment of membrane potential, the elevation of intracellular calcium and the upregulation of NOS, ET-1 and VEGF expressions, which are induced by Acrolein[3]. |
---|
In Vivo | Cesium Chloride (12 mg/100 g body weight, daily for 30 days; i.p.; male Wistar rats- BOO model) could significantly weaken the effect of XJT (traditional Chinese medicine) on not only the expression of these potassium channels but also the bladder weight, urodynamics, and oxidative stress[1]. |
---|
References | [1]. Sun J, Shen W, et al. A Chinese Medicine Formula "Xian-Jia-Tang" for Treating Bladder Outlet Obstruction by Improving Urodynamics and Inhibiting Oxidative Stress through Potassium Channels. Evid Based Complement Alternat Med. 2017;2017:8147258. [2]. Soto C, et al. Alloxan decreases intracellular potassium content of the isolated frog skin epithelium. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130(1):19-27. [3]. Ouyang JS, Li YP, Li CY, et al. Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. Free Radic Res. 2012;46(12):1437-1445. [4]. O'Brien CE, et al. Cesium-induced QT-interval prolongation in an adolescent. Pharmacotherapy. 2008;28(8):1059-1065. |
---|
Chemical & Physical Properties
Density | 3.983 |
---|
Boiling Point | 1290 °C |
---|
Melting Point | 645 °C(lit.) |
---|
Molecular Formula | CsCl |
---|
Molecular Weight | 168.359 |
---|
Flash Point | 1303°C |
---|
Exact Mass | 167.874298 |
---|
Index of Refraction | 1.6418 |
---|
Stability | Stable. Deliquescent. Incompatible with strong oxidizing agents, strong acids. Protect from moisture. |
---|
Water Solubility | 1860 g/L (20 ºC) |
---|
MSDS
Cesium chloride MSDS(Chinese) |
Toxicological Information
CHEMICAL IDENTIFICATIONCHEMICAL NAME : Cesium chloride
CAS REGISTRY NUMBER : 7647-17-8
HEALTH HAZARD DATAACUTE TOXICITY DATASPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2600 mg/kg
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1500 mg/kg
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2306 mg/kg
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1460 mg/kg
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
MUTATION DATATEST SYSTEM : Rodent - mouse
REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 244,295,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3874 No. of Facilities: 189 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 3353 (estimated) No. of Female Employees: 1792 (estimated)
|
Safety Information
Symbol | GHS08 |
---|
Signal Word | Warning |
---|
Hazard Statements | H361 |
---|
Precautionary Statements | P280 |
---|
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|
Hazard Codes | Xn:Harmful |
---|
Risk Phrases | R68 |
---|
Safety Phrases | S36/37-S26 |
---|
RIDADR | 2923 |
---|
WGK Germany | 2 |
---|
RTECS | FK9625000 |
---|
HS Code | 28273980 |
---|
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Email address : Sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 86 13526505137