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ChemicalBook Product Catalog Chemical Reagents Organic reagents Aromatic ketones 3'-Hydroxyacetophenone

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3'-Hydroxyacetophenone NEW

$0.10 1000KG

$5.00 1KG

Min. Order1KG
Purity99%
Cas No121-71-1
Supply Abilityg-kg-tons, free sample is available
Update time2024-04-16

Henan Fengda Chemical Co., Ltd

1YR

China

Since2023-02-10

AddressRoom 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro

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Chemical Properties

Product Name	3'-Hydroxyacetophenone
CAS No	121-71-1
EC-No
Min. Order	1KG
Purity	99%
Supply Ability	g-kg-tons, free sample is available
Release date	2024/04/16

1. Materials information

Names

Name	3'-Hydroxyacetophenone
Synonym	More Synonyms

3-ACETYLPHENOL Biological Activity

Description	3-Hydroxyacetophenone (m-Hydroxyacetophenone) is the hydroxy-substituted alkyl phenyl ketone that can be used in synthesis of enantiopure (-)-rivastigmine[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Katharine Moore Tibbetts, et al. Controlling dissociation of alkyl phenyl ketone radical cations in the strong-field regime through hydroxyl substitution position. J Phys Chem A. 2014 Sep 18;118(37):8170-6. [2]. Kiwon Han, et al. Chemoenzymatic synthesis of rivastigmine via dynamic kinetic resolution as a key step. J Org Chem. 2010 May 7;75(9):3105-8.

Description

3-Hydroxyacetophenone (m-Hydroxyacetophenone) is the hydroxy-substituted alkyl phenyl ketone that can be used in synthesis of enantiopure (-)-rivastigmine[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Katharine Moore Tibbetts, et al. Controlling dissociation of alkyl phenyl ketone radical cations in the strong-field regime through hydroxyl substitution position. J Phys Chem A. 2014 Sep 18;118(37):8170-6.

[2]. Kiwon Han, et al. Chemoenzymatic synthesis of rivastigmine via dynamic kinetic resolution as a key step. J Org Chem. 2010 May 7;75(9):3105-8.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	277.0±23.0 °C at 760 mmHg
Melting Point	90-95 °C(lit.)
Molecular Formula	C8H8O2
Molecular Weight	136.148
Flash Point	115.8±15.2 °C
Exact Mass	136.052429
PSA	37.30000
LogP	1.39
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.552

MSDS

3-ACETYLPHENOL MSDS(Chinese)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25-S37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2914399090

Synthetic Route

Previous 1/12 Next

3'-Methoxya...

586-37-8

~94%

3-ACETYLPHENOL

121-71-1

Literature: Park, Jiyeon; Chae, Junghyun Synlett, 2010 , # 11 p. 1651 - 1656

m-Bromoacetophe...

2142-63-4

~98%

3-ACETYLPHENOL

121-71-1

Literature: Anderson, Kevin W.; Ikawa, Takashi; Tundel, Rachel E.; Buchwald, Stephen L. Journal of the American Chemical Society, 2006 , vol. 128, # 33 p. 10694 - 10695

1-(3-ethoxyphen...

52600-91-6

~96%

3-ACETYLPHENOL

121-71-1

Literature: Park, Se Kyung; Battsengel, Oyunsaikhan; Chae, Junghyun Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 1 p. 174 - 178

Precursor & DownStream

Precursor 10	Previous 1/3 Next
CAS#:586-37-8 3'-Methoxyaceto... CAS#:2142-63-4 m-Bromoacetophenone CAS#:52600-91-6 1-(3-ethoxyphen... CAS#:124414-07-9 1-[3-[tert-buty...
DownStream 10	Previous 1/3 Next
CAS#:111651-85-5 1-(3-hexoxyphen... CAS#:110718-87-1 1-(2-iodo-5-met... CAS#:105805-17-2 2-(2-bromo-5-ph... CAS#:34068-01-4 3-Benzyloxy ace...

Customs

HS Code	2914501900
Summary	2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles6

Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins

Bioorg. Med. Chem. 17 , 896-904, (2009)

This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoret...

Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.

J. Med. Chem. 54 , 211-221, (2011)

Folate analogue inhibitors of Leishmania major pteridine reductase (PTR1) are potential antiparasitic drug candidates for combined therapy with dihydrofolate reductase (DHFR) inhibitors. To identify n...

Synthesis of new UV-B light absorbents: (Acetylphenyl)glycosides with antioxidant activities.

Bioorg. Med. Chem. Lett. 18 , 3582-4, (2008)

m-Acetylphenyl-beta-d-glucopyranosides and m-acetylphenyl-alpha/beta-d-mannopyranosides were synthesized by the Koenigs-Knorr, Mitsunobu, and Helferich reactions as key glycosylation reactions, respec...

Synonyms

3-Hydroxyphenyl Methyl Ketone

3-Hydroxyacetophenone

3-HYDROXY-ACETOPHENONE

Ethanone, 1-(3-hydroxyphenyl)-

Ethanone, 1- (3-hydroxyphenyl)-

3’-Hydroxyacetophenone

3-Acetophenol

EINECS 204-494-0

m-Acetylphenol

3-ACETYLPHENOL

3‘-Hydroxyacetophenone

1-(3-Hydroxyphenyl)ethanone

3′-Hydroxyacetophenone

MFCD00002298

2. Packaging of materials

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

3. Shipping & Delivery

By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 13213167925

WhatsApp/Skype/Wechat/LINE: 86 13213167925

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Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.