名称 | γ-1-MSH, amide acetate (72629-65-3 free base) |
描述 | γ-1-MSH, amide acetate (72629-65-3 free base), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. |
体外活性 | γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) balance, and blood pressure regulation. γ-MSH is processed from the precursor hormone pro-opio-melanocortin (POMC) in the pituitary gland, where component peptides are released into the cerebral spinal fluid and systemic circulation. The natural receptor for γ-MSH is the melanocortin receptor 3 (MC3-R), a G-protein-coupled receptor that activates adenylate cyclase and is expressed in brain (hypothalamus, cortex, and thalamus), gut, placenta, and kidney. γ-MSH regulates Na+ balance by inducing urinary Na+ excretion (natriuresis) under conditions of high dietary salt intake[1]. |
存储条件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 10 mM
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关键字 | r-1-MSH, amide Acetate | γ 1 MSH, amide acetate (72629 65 3 free base) | gamma-1-MSH, amide Acetate | γ1MSH, amide acetate (72629653 free base) | γ-1-MSH, amide Acetate | 72629-65-3 free base | 72629-65-3 |
相关库 | 经典已知活性库 | 多肽分子库 | NO PAINS 化合物库 | 已知活性化合物库 | 抗癌化合物库 | 抗癌活性化合物库 |