3-Trimethylsilyl-2-propynylcopper(I) is a agent for the introduction of the trimethylsilylpropynyl group via 1,6-conjugate additions and vinyl substitutions; preparation of lithium bis(trimethylsilylpropynyl)cuprate.
A solution of 1-lithio-3-trimethylsilyl-
1-propyne containing N,N,N,N
-tetramethylethylenediamine
(TMEDA) in ether or THF is added to a slurry of copper(I)
iodide in ether at ?78°C, then warmed to ?10°C and used
immediately.
