2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one

2-MPMDQ is a novel class of α1-adrenoceptor antagonists and acts as an anti-hypertensive agent.

ChEBI: 2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5-one is a member of piperazines.

Potent and selective α 1 -adrenoceptor antagonist; hypotensive.

α1-adrenergic receptor: 0.37 nM (Ki); α2-adrenergic receptor: 1740 nM (Ki)

[1]. chern jw, tao pl, yen mh, et al. studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. j med chem, 1993, 36(15): 2196-2207.