NBD sphingosine-1-phosphate has been used as a substrate in the detection of sphingosine-1-phosphate phosphatases (SPPase) enzymatic activity by in vitro assay.
Biological Activity
Sphingosine-1-phosphate (S1P) initiates DNA synthesis. It is also involved in cell division, cell growth and platelet activation. S1P mediates cell movement, differentiation and survival. It specifically stimulates endothelial cells.