2,6-Dimethylphenylpropionate is used as an intermediate in the Saliniketal A, B formal synthesis desymmetrization.
2,6-Dimethylphenyl Propionate is prepared in excellent yield by the reaction of the sodium or lithium salt of
2,6-dimethylphenol with propionyl chloride.[1a,1b]
2,6-Dimethylphenyl Propionate is a lithium, titanium, and zirconium enolates used in the stereoselective synthesis of anti or syn β-hydroxy acid
derivatives.
1. (a) Montgomery, S. H.; Pirrung, M. C.; Heathcock, C. H. OS 1985, 63, 99; OSC 1990, 7, 190. (b) Heathcock, C. H.;
Pirrung, M. C.; Montgomery, S. H.; Lampe, J. T 1981, 37, 4087
