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2-(2-aminoethyl)phenol

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2-(2-aminoethyl)phenol Basic information
2-(2-aminoethyl)phenol Chemical Properties
  • storage temp. Keep in dark place,Inert atmosphere,2-8°C
2-(2-aminoethyl)phenol Usage And Synthesis
  • Description2-Hydroxyphenethylamine (also known as phenylethanolamine) is a kind of trace amine found in the brain. It may modulate the sympathetic functions. It has strong cardiovascular activity, and can be used as a drug to produce topical vasoconstriction. Its derivatives are adrenergic agonists and antagonists, and have the potential for the treatment of respiratory diseases.
  • Uses2-(2-aminoethyl)phenol is a ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoa mine oxidase B and was revealed to be a potential inactivator of MAO-B.
  • Synthesis Reference(s)The Journal of Organic Chemistry, 41, p. 2502, 1976 DOI: 10.1021/jo00876a038
  • Referenceshttps://en.wikipedia.org/wiki/Phenylethanolamine
    Biggadike, Keith, et al. "PHENYLETHANOLAMINE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES." WO, EP 1556340 A1. 2005.
    https://pubchem.ncbi.nlm.nih.gov/compound/2-Amino-1-phenylethanol#section=Top
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