Difloxacin-d3

Difloxacin-d₃ is intended for use as an internal standard for the quantification of difloxacin by GC- or LC-MS. Difloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, including B. fragilis, as well as Fusobacterium and Actinomyces species with MIC values ranging from ≤0.125 to 8 μg/ml. It eliminates E. coli and B. fragilis infection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.

Difloxacin-d3 (methyl-d3) (CAS# 1173147-93-7) is a useful isotopically labeled research compound.