3-Methoxy-17,21-[(1-methylethylidene)bis(oxy)]-pregna-3,5-dien-20-one is an intermediate in the synthesis of 6α-Hydroxy-11-deoxycortisol (H934905). 6α-Hydroxy-11-deoxycortisol is a corticosteroid which is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids.