Air and thermally stable, one-component precatalyst for the amination of aryl halides.
2-(2′-Di-tert-butylphosphine)biphenylpalladium(II) Acetate is a precatalyst for Buchwald-Hartwig amination reaction. It is also used to prepare anticancer LPA2 antagonists.
It can be used as a pre-catalyst for the amination of aryl chlorides. It can also be used to prepare N-methyl-6-heterocyclic-1-oxoisoindoline derivatives via Buchwald-Hartwig amination reaction of N-methyl-6- bromoisoindoline-1-one with different amines under microwave condition.
2-(2′-Di-tert-butylphosphine)biphenylpalladium(II) acetate is a novel, air- and moisture-and thermally stable catalyst.
