3-Ethoxyestra-3,5-dien-17-one is used in steroidal studies such as the search to increase progestin activity, in which 3-Ethoxyestra-3,5-dien-17-one was a reactant in synthesizing 17α-acetoxy-6,21-dimethyl-3,20-dioxo-19-norpregna-4,6-diene, a new compound.