α-[2-(2,4-Difluorophenyl)-2-oxoethyl]-1H-indole-3-acetic Acid, is a derivative of the plant hormone indole-3-acetic acid, improves survival of fibroblasts from patients with mitochondrial diseases.
Mitochonic Acid 5 is a potent enhancer of mitochondrial ATP production th at significantly increased the cellular ATP level in Hep3B human hepatocellular carcinoma cells. Mitochonic Acid 5 improves the survival of fibroblasts from patients with mitochondrial diseases. It appears th at mitochonic Acid 5 facilitates ATP synthase oligomerization and supercomplex formation with mitofilin/Mic60.