C6 dihydro 1-Deoxyceramide (m18:0/6:0)

C6 dihydro 1-Deoxyceramide (m18:0/6:0) is a short-chain atypical ceramide containing a 1-deoxysphinganine (m18:0) (Item No. 13511) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2WARNING This product is not for human or veterinary use.

[1] REGULA STEINER. Elucidating the chemical structure of native 1-deoxysphingosine.[J]. Journal of Lipid Research, 2016, 57 7: 1194-1203. DOI: 10.1194/jlr.m067033
[2] I. ALECU. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway[S][J]. Journal of Lipid Research, 2016, 58 1: 60-71. DOI: 10.1194/jlr.m072421