[4-(pyrimidin-2-yloxy)cyclohexyl]amine

Trans-4-(Pyrimidin-2-yloxy)cyclohexanamine is used as a reactant in the preparation of (S)-N-(N-cyclohexylglycyl)pyrrolidine-2-carbonitriles and (R)-N-(N-cyclohexylglycyl)thiazolidine-2-carbonitriles as dipeptidyl peptidase IV inhibitors for prevention or treatment of diabetes.