Kansuinine B

Kansuinine B shows cytotoxic activity. Kansuinine B shows analgesic activity. 3. Treatment with kansuinine B and kansuinine A represents a novel method to block the IL-6-induced effects.

Kansuinine B inhibits IL-6-induced Stat3 activation. Kansuinine B possesses anti-viral activity and could be used in the study for COVID-19[1][2][3].

ChEBI: Kansuinine B is a benzoate ester.

IL Receptor | STAT | ERK | MEK

[1] Jong Sun Chang, et al. Kansuinine A and Kansuinine B from Euphorbia kansui L. inhibit IL-6-induced Stat3 activation. Planta Med. 2010 Oct;76(14):1544-9. DOI:10.1055/s-0030-1249805
[2] Xiaoyun Shu, et al. Bioassay-guided separation of the proinflammatory constituents from the roots of Euphorbia kansui. J Nat Med. 2010 Jan;64(1):98-103. DOI:10.1007/s11418-009-0366-0
[3] YASER DAANIAL , et al. PROMISING COMPOUNDS FOR TREATMENT OF COVID-19. VAWKUM Transactions on Computer Sciences, ISSN(e):2308-8168, ISSN(p): 2411-6335. Volume 17, Number 1, January-June, 2020.