15(S)-15-methyl Prostaglandin F2α ethyl amide

15(S)-15-methyl Prostaglandin F2α has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor.1,2 15(S)-15-methyl PGF2α ethyl amide is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester. Prostaglandin esters are generally hydrolyzed to the free acid upon in vivo administration, making the methyl esters useful prodrugs.3 Hydrolysis of prostaglandin amides in vivo is not thoroughly established.WARNING This product is not for human or veterinary use.

[1] MD S.J. CARLAN . Effect of intramuscular 15-methyl prostaglandin F2α after second-trimester delivery[J]. Obstetrics and gynecology, 1997, 89 1: Pages 5-9. DOI: 10.1016/s0029-7844(96)00433-4
[2] LINDBLOM B. Local prostaglandin F(2alpha) injection for termination of ectopic pregnancy[J]. International Journal of Gynecology & Obstetrics, 1988, 26 2: Page 335. DOI: 10.1016/0020-7292(88)90306-2
[3] WILLIAM L. MILLER  Mary J S. Relative biological activity of certain prostaglandins and their enantiomers[J]. Prostaglandins, 1976, 11 1: Pages 77-84. DOI: 10.1016/0090-6980(76)90175-1