Insulin-like growth factor-I receptor human has been used to study the binding constants of estradiol to insulin, insulin receptors and insulin-like peptides.
Biological Activity
IGF-I receptor, a tyrosine kinase receptor with signal transduction pathways, is comprised of two α and two β subunits. IGF-I receptor binds IGF-I with high affinity, IGF-II with lower affinity, and insulin with weak affinity.
