(±)-Clorprenaline-d
7 is intended for use as an internal standard for the quantification of clorprenaline by GC- or LC-MS. Clorprenaline is a β
2-adrenergic receptor agonist.
1 It reverses pilocarpine-induced constriction of isolated guinea pig trachea, rabbit lung, and bronchi of pithed dogs.
2 It has been detected in pork, beef, mutton, and chicken muscle food samples by UPLC-Q-orbitrap-HRMS.
1 Formulations containing clorprenaline have been used as partitioning agents and growth promoters in livestock.
1. Guo, C., Shi, F., Gong, L., et al. Ultra-trace analysis of 12 β2-agonists in pork, beef, mutton and chicken by ultrahigh-performance liquid-chromatography-quadrupole-orbitrap tandem mass spectrometry J. Pharm. Biomed. Anal. 107,526-534(2015).
2. Powell, C.E., Gibson, W.R., and Swanson, E.E. The pharmacological action of 1-o-chlorophenyl-2-isopropylaminoethanol (isoprophenamine); A bronchodilator J. Am. Pharm. Assoc. 45(12),785-787(1956).
