胃动素
胃动素 性质
| 储存条件 | −20°C |
|---|---|
| 溶解度 | 25mg/mL，溶于 DMSO 和 DMF，微溶于乙醇 |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| 水溶解性 | Soluble to 1 mg/ml in water |
| 序列 | Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Met-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln |
胃动素 用途与合成方法
EC50: 0.3 nM (motilin receptor, Chinese hamster ovary cell)
Ki: 2.3 nM (motilin receptor, Chinese hamster ovary cell)
[Bpa 1 ,Ile 13 ]motilin is a full agonist at the motilin receptor that increases intracellular calcium in a concentration-dependent manner (EC 50 = 1.5 ± 0.4 nM). Motilin binds with high affinity (IC 50 0.7± 0.2 nM) to receptors on smooth muscle cells. Motilin selectively activates G(q) and G(13), stimulates G alpha(q)-dependent phosphoinositide (PI) hydrolysis and 1,4,5-trisphosphate (IP(3))-dependent Ca 2+ release, and increases cytosolic free Ca 2+ . Motilin induces a biphasic, concentration-dependent contraction (EC 50 = 1.0 +/- 0.2 nM), consisting of an initial peak followed by a sustained contraction.
胃动素 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-06-05 | HY-P1037 | 胃动素 | 52906-92-0 | 500μg | 580 |
| 2026-06-05 | HY-P1037 | 胃动素 | 52906-92-0 | 1mg | 923 |
