β-CGRP, human TFA
中文名称:β-CGRP, human TFA
英文名称:β-CGRP, human TFA
CAS号:
分子式:C???H???F?N??O??S?
分子量:0
EINECS号:
Mol文件:Mol File
β-CGRP, human TFA 用途与合成方法
β-CGRP, human TFA (Human β-CGRP TFA) 是一种降钙素肽，通过降钙素受体样受体 CRLR 与 RAMP 的复合物起作用，在细胞体系中，对 CRLR/RAMP1 和 CRLR/RAMP2 的 IC50 值分别为 1 nM 和 300 nM。
IC50: 1 nM (CRLR/RAMP1, cell assay), 300 nM (CRLR/RAMP2, cell assay)
β-CGRP, human is one of calcitonin peptides, acts via complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC 50 s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 130 nM and 300 nM in NG108-15 and HEK293T cells expressing CRLR and RAMP2. CGRP is a potent vasodilator and also shows pro- and -anti-inflammatory activity.
