BAY-677 is the negative control probe for
BAY-678, which is a human neutrophil elastase (HNE) inhibitor with >2,000-fold selectivity for HNE over a panel of 21 other serine proteases. For characterization details of BAY-678 and BAY-677, please visit the
BAY-677 probe summary on the Structural Genomics Consortium (SGC) website.
BAY-678, the active HNE probe, is available from Sigma. To learn more about and purchase BAY-678,
click here.
To learn about other SGC chemical probes for protein targets, visit
sigma.com/sgc