(4-ethylnaphthalen-1-yl)-[1-(5-hydroxypentyl)indol-3-yl]methanone

JWH 210 is a potent cannabimimetic alkylindole that has been identified in extracts from herbal blends. Structurally and functionally similar alkylindoles are rapidly metabolized by the liver and secreted in the urine, with 5-carboxypentyl metabolites detected in the urine.^1,2,3 JWH 210 N-(5-hydroxypentyl) metabolite is an expected metabolite of JWH 210, detectable in the serum and urine. Its biological activities have yet to be determined. This product is intended for forensic purposes.

JWH-210 (Indole-d5) 5-Hydroxypentyl JWH-210 5-Hydroxypentyl (J211490) which is a urinary metabolite of JWH-210, an analgesic chemical that acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors.

1. Teske, J., Weller, J.P., Fieguth, A., et al. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878(27),2659-2663(2010).
2. Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine Forensic Sci. Int. 200(1-3),141-147(2010).
3. Wintermeyer, A., Mller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).