Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and
over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through
Aldrich Market Select.
This hindered amine was accessed via a recent publication reported by
Baran and coworkers using an innovative hydroamination method.
