2-(Azido-PEG2-amido)-1,3-propandiol is a branched PEG derivtive containing terminal azide moieties and two primary alcohol groups. The azide group can participate in copper-catalyzed Click Chemistry reactions with alkyne, DBCO and BCN moieties. The hydroxyl groups can react to further derivatize the compound. PEG linker increases solubility of compounds in aqueous media.
2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2-(Azido-PEG2-amido)-1,3-propandiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
