Talin 2 is a protein encoded by the TLN2 gene in humans and belongs to the talin protein family. It plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. Talin 2 also plays a crutial role in cell adhesion and recycling of synaptic vesicles. It may help in serving as a link between integrins and the sarcomeric cytoskeletonin stable adhesion complexes in mature striated muscle.