(1’S,2’S)-Nicotine 1’-Oxide-d3, is a labeled analogue of (1’S,2’S)-Nicotine 1’-Oxide (N427500). which is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man.