基本属性 生物活性体外研究体内研究 用途与合成方法 供应商

BETAMETHASONE HYDROCHLORIDE

BETAMETHASONE HYDROCHLORIDE

英文名称:BetaMethasone (hydrochloride)
CAS号:956901-32-9
分子式:C28H38ClFO7
分子量:541.0485232
EINECS号:
Mol文件:956901-32-9.mol
BETAMETHASONE HYDROCHLORIDE 结构式

BETAMETHASONE HYDROCHLORIDE 性质

储存条件 Store at -20°C
溶解度 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。
形态 粉末

BETAMETHASONE HYDROCHLORIDE 用途与合成方法

Betamethasone hydrochloride 是一种合成糖皮质激素,具有抗炎和免疫抑制活性。Betamethasone hydrochloride 可加速胎儿肺成熟并诱导基因表达和细胞凋亡。

Betamethasone (0.1-1 μM; 12 h) induces gene expression in L929 cells.
Betamethasone (0.1-1 μM; 48 h) induces CEM C7 T-cells apoptosis.

Betamethasone (0.48 mg; i.v.gtt for 48 h) decreases the hypercapnia-induced increase in CBF due to decreased cerebral vasodilatation. Betamethasone (0.05 ml (1 mg/L); topical injection) ameliorates spinal nerve transection induced mechanical allodynia and thermal hyperalgesia, and reduces the activation of NF-κB and elevation of TNFα and IL-1β, and induces the expression of IL-10 in the rats brain.

Animal Model: Rambouillet-Colombia ewes bred on a single occasion are received hypercapnic challenges
Dosage: 0.48 mg
Administration: Injected into the fetal jugular vein at a rate of 1 ml/h (10 μg betamethasone/h) and maintained over the next 48 h.
Result: Decreased cerebral blood flow (CBF) in all brain regions measured except the hippocampus after 24 h of infusion.
The reduction in CBF was diminished to about 25-30 % after 48 h of infusion.

BETAMETHASONE HYDROCHLORIDE供应商 更多

北京普西唐生物科技有限公司
联系电话:010-60605840 18892239720
产品介绍:
中文名称:盐酸倍他米松
英文名称:Betamethasone hydrochloride
CAS:956901-32-9
纯度:98%
包装信息:100mg;250mg;500mg
爱必信(上海)生物科技有限公司
联系电话:021-38015121 15000105423
产品介绍:
英文名称:Betamethasone hydrochloride
CAS:956901-32-9
纯度:98%
包装信息:500mg;100mg
天津普西唐生物医药科技有限公司
联系电话:010-60605840 15801484223;
产品介绍:
中文名称:盐酸倍他米松
英文名称:Betamethasone hydrochloride
CAS:956901-32-9
纯度:98%
包装信息:100mg;250mg;500mg
銳迪國際科技有限公司
联系电话: 18024082417
产品介绍:
英文名称:Betamethasone hydrochloride
CAS:956901-32-9
纯度:5mg;10mg;50mg;100mg;250mg;500mg;1g
包装信息:5mg;10mg;50mg;100mg;250mg;500mg;1g