S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺
S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺
![S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 结构式](https://img.chemicalbook.com/CAS/20150408/GIF/21306-65-0.gif)
S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 性质
| 沸点 | 587.6±60.0 °C(Predicted) |
|---|---|
| 密度 | 1.22±0.1 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | 二甲基亚砜：>30mg/mL |
| 形态 | 白色粉末 |
| 颜色 | 白色 |
S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 用途与合成方法
The Pirin is a nuclear protein with the nuclear factor I/CCAAT box transcription factor (NFI/CTF). Pirin proteins are highly conserved between mammals, plants, fungi, and prokaryotic organisms and are considered to belong to the cupin superfamily.TPh A (20 μM; 5 hours) reduces the amount of pirin-bound Bcl3 and inhibits the interaction between pirin and Bcl3 in HEK293T cells in a glutathione S-transferase (GST) pulldown assay (HEK293T cells are transfected with vectors that encoded bcl3-Myc and pirin-His6 for 43 h of transfection).TPh A (0-100 μM; 48 hours) does not exert any potent cytotoxic activity against many human cancer cell lines, it against MCF7, MDA-MB231, HeLa, DU145, HepG2, A549, HT1080, WM266-4, and SK-MEL-28 cells with IC 50 values >50 μM, and exhibits IC 50 values of 27 μM, 20 μM and 26 μM for PC3 HL60 and HT29 cells, respectively.TPhA (0-50 μM; 48 hours) inhibits cell migration in WM266-4 cells, SK-MEL-28 cell in a concentration-dependent manner.
Cell Viability Assay
| Cell Line: | MCF7, MDA-MB231, HeLa, DU145, HepG2, A549, HT1080, WM266-4, and SK-MEL-28 cells |
| Concentration: | 0-100 μM |
| Incubation Time: | 48 hours |
| Result: | Did not exert any potent cytotoxic activity against many human cancer cell lines. |
S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-14454 | S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 | 21306-65-0 | 5mg | 1000 |
| 2024-11-08 | HY-14454 | S-[4-(苄氧基)苯基]-S-甲基-N-(对甲苯基磺酰基)-硫亚胺 | 10 mM * 1 mLin DMSO | 1100 |
