5-Hydroxypentanoic Acid SodiuM Salt

542-28-9

37435-69-1

General procedure for the synthesis of sodium 5-hydroxyvalerate from tetrahydro-2H-pyran-2-one: Tetrahydro-2H-pyran-2-one (1.0 g, 10 mmol) was added to a 90% ethanol solution (23 mL) containing NaOH (0.44 g, 11 mmol). The reaction mixture was stirred at 80°C for 30 minutes, followed by continued stirring at room temperature for 2 hours. Upon completion of the reaction, the excess solvent was removed by distillation under reduced pressure to quantitatively obtain sodium 5-hydroxyvalerate.