(S)-2-Diphenylmethylpyrrolidine (hydrochloride)

(S)-Desoxy-D2PM (hydrochloride) is most commonly used as a chiral solvating agent for NMR analysis of chiral compounds. Interestingly, it is also, structurally, closely related to 2-DPMP (hydrochloride) , a dopamine transporter inhibitor and psychoactive stimulant. The physiological and toxicological properties of (S)-Desoxy-D2PM have not been explored.

The hydrochloride salt of a useful chiral auxiliary (2S)-2-(Diphenylmethyl)pyrrolidine, based on (S)-proline and bearing sterically demanding side chains at the pyrrolidine moiety.