PGE2, a member of the prostaglandin family, is a bioactive lipid molecule produced by cyclooxygenase. Its increased endometrial biosynthesis induces labor and dysmenorrhea. In cardiovascular and immune systems, it enhances the inflammation triggered by leukotrienes. PGE2 can inhibit the release of mediators, as well as regulate monocyte-macrophages and dendritic cells. Anti-Prostaglandin E2 antibody can be used to quantify PGE by radioimmunoassay. Rabbit anti-Prostaglandin E2 antibody reacts with PGE2 and PGE1.
