The alkaloid originally isolated under this name by Aston proved to be a
mixture of laureline and pukateine and the name was then given to a third alkaloid occurring in the bark of Laurelia Novae-Zelandae. The base crystallizes in
colOUrless needles or hexagonal tablets and is laevorotatory with [α]D - 222°
(CHCl 3 ). The sulphate hexahydrate, m.p. 99-l00°C is almost completely insoluble in H20; the methiodide has m.p. 249-250°C and the O,G-dimethyl
ether forms colourless prisms, m.p. l34°C, b.p. 200-2l0°C/l0 mm; [α]D - 314°
(CHC13). The probable structure, given above, has been deduced by comparison
with other, similar alkaloids although the alternative structure 3 :4-dihydroxy-
6:7-methylenedioxyaporphine, is not completely excluded.
Aston.,J. Chem. Soc., 97, 1381 (1910)
Barger, Girardet., Helv. Chim. Acta., 14, 481 (1931)
Girardet., ibid, 14, 504 (1931)
Govindachari et al., Chem. Ber., 91, 36 (1958)