2,2-diethoxyacetaldehyde

2,2-diethoxyacetaldehyde is used as a reagent for preparation of α,β-unsaturated aldehydes1-8 and heterocyclic compounds.

preparations of 2,2-diethoxyacetaldehyde usually involve either oxidative cleavage of glyceraldehyde acetals, or reductive ozonolysis of acrolein or crotonaldehyde dialkyl acetals.

Synthetic Communications, 17, p. 1807, 1987 DOI: 10.1080/00397918708077325

2,2-diethoxyacetaldehyde should be stored under inert gas and at low temperature.