(L)-2-[(T-Boc)Amino]-2-[(5-Fluoresceinyl)Aminocarbonyl]Ethyl Methanethiosulfonate is a thiol specific fluorescent probe useful for ion channel and protein topology research. The recently available MTS-fluorophores may find application in the real-time monitoring of conformational cha nges, since fluorophores coupled to introduced cysteines can change their fluorescence during a conformational change. Fluorescence lifetime may also yield information regarding distances and molecul ar motion in a protein molecule. Fluorescence: max. Abs. 492nm; max. Em. 515nm; e x 10-3: 75