TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt)

TAMRA-Amyloid-β (1-42) peptide is a fluorescently labeled peptide. Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-residue protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer’s disease.1,2 Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers.1 TAMRA-Amyloid-β (1-42) peptide is a labeled form of Aβ42 containing carboxytetramethyl rhodamine (TAMRA), which displays excitation/emission maxima of 543/572 nm, respectively.WARNING This product is not for human or veterinary use.

[1] WAHLUND L, COWBURN R, WINBLAD B, et al. Therapeutic Strategies in Alzheimer’s Disease[C]. 1900: 0. DOI: 10.1007/978-1-4615-8149-9_80
[2] T IWATSUBO. Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).[J]. Neuron, 1994, 13 1: 45-53. DOI: 10.1016/0896-6273(94)90458-8