AZD-PEG5 -PFP

AZD-PEG5-PFP is a PEG linker containing an AZD group and a PFP ester group, an activated ester that reacts with primary amines to form amide bonds. PFP ester has been found to be more stable than other amine reactive groups because it is less likely to undergo hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.