S-(3-二甲氨基丙基)异硫脲二盐酸盐
S-(3-二甲氨基丙基)异硫脲二盐酸盐 性质
| 储存条件 | Desiccate at RT |
|---|---|
| 溶解度 | H2O：≥50mg/mL |
| 形态 | 粉末 |
| 颜色 | 白色至类白色 |
| 水溶解性 | Soluble to 100 mM in water |
| InChI | 1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H |
| InChIKey | DFWCPLGXFMSUCW-UHFFFAOYSA-N |
| SMILES | Cl.Cl.CN(C)CCCSC(N)=N |
S-(3-二甲氨基丙基)异硫脲二盐酸盐 用途与合成方法
|
H 2 Receptor
|
nNOS 49 μM (IC 50 ) |
Dimaprit has less than 0.0001% the activity of histamine on H1-receptors.
Dimaprit (0.1 nM-100 μM) inhibits nNOS concentration dependently with an IC
50
of 49±14 μM.
Dimaprit stimulates gastric acid secretion in rats (1.25 μM/kg/min; rapid i.v. injection), cats (2-64 μM/h; i.v.) and dogs (1-100 nM/kg/min; i.v.).
Dimaprit (0.01-1 μM/kg; i.v. at intervals of 5 min) causes dose-dependent falls in blood pressure in cats. Dimaprit (1-100 nM; intra-arterial injection) causes vasodilatation in the femoral vascular bed, and it (1 μM/kg; bolus or intravenous injection) has no effect on heart rate.
安全信息
| 危险品标志 | Xi |
|---|---|
| 危险类别码 | 36/37/38 |
| 安全说明 | 26-36 |
| WGK Germany | 3 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 眼部刺激 类别2 经皮刺激 类别2 特异性靶器官毒性-一次接触，类别3 |
S-(3-二甲氨基丙基)异硫脲二盐酸盐 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-B1478 | S-(3-二甲氨基丙基)异硫脲二盐酸盐 | 23256-33-9 | 25 mg | 600 |
| 2026-09-15 | HY-B1478 | S-(3-二甲氨基丙基)异硫脲二盐酸盐 | 23256-33-9 | 10 mM * 1 mLin DMSO | 660 |
