Diclofenac Related Compound 1

2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid is a related compound of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. 2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid can be used to study cytochrome P 450 isoforms involved in the bioactivation of diclofenac to reactive p-benzoquinone imines (4).

ChEBI: 4'-hydroxydiclofenac quinone imine is a quinone imine that is a metabolite of diclofenac arising from 4'-hydroxylation followed by oxidation. It has a role as a metabolite. It is a quinone imine and an organochlorine compound. It is functionally related to a diclofenac.