1-Cyclopentylpiperazine-d9 Dihydrochloride is an intermediate in the synthesis of 1-Cyclopentyl-4-nitrosopiperazine-d9 (C213797), an isotopically labeled compound of 1-Cyclopentyl-4-nitrosopiperazine (C213795). 1-Cyclopentyl-4-nitrosopiperazine is used in the green preparation of aminoazacyclic compounds via a new method of selective reduction.