Fmoc-D-Aha-OH

White crystalline powder

Fmoc-D-Aha-OH is a click chemistry reagent containing an azide[1]. Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

[1] Millward SW, et al. Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1. J Am Chem Soc. 2011 Nov 16;133(45):18280- DOI:10.1021/ja2064389