JWH 081-d
9 (exempt preparation) is intended for use as an internal standard for the quantification of JWH 081 by GC- or LC-MS. JWH 081 is categorized as a synthetic cannabinoid.
1,2 It has been found in Spice/K2-type herbal blends and may have neurotoxic properties.
3 JWH 081 is regulated as a Schedule I compound in the United States. JWH 081-d
9 (exempt preparation) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
[1] Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2),133-140(2000).
[2] Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists Bioorg. Med. Chem. 13(1),89-112(2005).
[3] Cha, H.J., Seong, Y.H., Song, M.J., et al. Neurotoxicity of synthetic cannabinoids JWH-081 and JWH-210 Biomol. Ther. (Seoul) 23(6),597-603(2015).
