(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

Product Name(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
CAS155899-66-4
MFC8H15NO3
MW173.21
EINECS692-595-4
MOL File155899-66-4.mol

Chemical Properties

Melting point	85-88℃
Boiling point	288℃
Density	1.170
Flash point	128℃
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	14.03±0.60(Predicted)
form	Solid
color	White to Pale Beige
Stability	Hygroscopic

Safety Information

HS Code

2932990090

Usage And Synthesis

Uses

(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol was used to preapare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis.

Preparation Products And Raw materials

Raw materials

4H-Cyclopenta-1,3-dioxol-4-ol, tetrahydro-2,2-dimethyl-6-[(phenylmethyl)amino]-, (3aR,4S,6R,6aS)-D-erythro-Pent-4-enitol, 1,4,5-trideoxy-2,3-O-(1-methylethylidene)-1-[oxido(phenylmethyl)imino]-, (1Z)-D-erythro-Pent-4-enose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI)4,7-Methano-4H-1,3-dioxolo[4,5-d][1,2]oxazine, tetrahydro-2,2-dimethyl-6-(phenylmethyl)-, (3aS,4S,7R,7aS)-(1R,3S)-4-CYCLOPENTENE-1,3-DIOL 1-ACETATE (3aS,4S,6R,6aR)-4-(iodoMethyl)-6-Methoxy-2,2-diMethyltetrahydrofuro[3,4-d][1,3]dioxole 2,2-Dimethoxypropane

Preparation Products