A further minor constituent of Pleiocarpa rnutica Benth, the base forms colourless crystals from CHC13-MeOH. It is strongly laevorotatory with [α]26D - 111 °
(c 1.93, CHC13), the ultraviolet spectrum in MeOH having absorption maxima at
230, 263, 285 and 292 mp.. The alkaloid is dimeric, the structure as determined
from chemical analysis and spectroscopic examination being 15-( 14'-
eburnamy1)p1eiocarpinine.
Kump, Schmid., Helv. Chirn. Acta, 44, 1503 (1961)
Structure and partial synthesis:
Thomas, Achenbach, Biemann., 1. Arner. Chern. Soc., 88, 1537 (1966)
![(2β,5β,12S,19β)-15-[14,15-Dihydroeburnamenin-14α-yl]-1-methylaspidofractinine-3α-carboxylic acid methyl ester Structure](/CAS/20211123/GIF/5263-34-3.gif)