This alkaloid occurs in Rhazya stricta and also in Vinca minor Decaisne. From
aqueous EtOH it crystallizes as the monohydrate with m.p. 80-3°C. It has
[α]24D+ 103° and gives an ultraviolet spectrum consisting of two absorption
maxima at 213 and 262 mfJ.. A methoxycarbonyl group and an alkyl groups are
present.
Cekan et al., Pharm. Acta Helv., 35,96 (1960)
Trojanek et al., Collect. Czech. Chem. Commun., 25, 2045 (1960)
Structure:
Schnoesetal.,J. Org. Chem., 31, 1641 (1966)