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1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE

Basic information Safety Related Supplier
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Basic information
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Chemical Properties
  • Melting point:110-112 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1))
  • storage temp. 2-8°C
Safety Information
  • WGK Germany 3
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Usage And Synthesis
  • Description1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.
  • Uses
    1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.
  • General Description
    1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.
  • Biochem/physiol ActionsInhibitor of glycogen phosphorylase and α-glucosidases.
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE(100991-92-2)Related Product Information
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDESupplierMore
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