This alkaloid of the pyrrolizidine group of bases occurs in Senecio cineraria D.C.,
S. crucifolia and S. Jacobea. It is a laevorotatory base with [α]17D - 46.3°
(CHCl 3 ). The alkaloid forms crystalline salts and derivatives, e.g. the hydrochloride, m.p. 220°C; [α]19D - 14.3° (H20); nitrate, m.p. 234°C; methiodide,
m.p. 255°C and the picrate, m.p. 180°C which is soluble in H20. The alkaloid
contains two active hydrogens and on alkaline hydrolysis yields retronecine and
jaconecic acid, ClOH16 0 6, m.p. 182°C; [α]25D + 31.7° containing three O-methyl
groups
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